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What You Need to Know About Peyronie’s Disease

patient at urologist
December 10, 2024

Welcome back to Balls Deep, where we tackle useful, and at times complex, aspects that involve men’s health. In Episode 29, Dr. Joe Pazona and his co-host Cat Williams address a condition known as Peyronie’s disease, a sexual disorder that is quite common but often misunderstood. Allow us to unpack their amusing yet enlightening discussion below:

What is Peyronie’s Disease?

Peyronie’s disease is a condition characterized by a significant curve in the penis during an erection, caused by scar tissue on the erectile chambers. While a slight angle is normal, Peyronie’s disease typically results in acquired curvature later in life and may interfere with sexual function.

How Does It Happen?

The exact cause of Peyronie’s disease isn’t always clear, but some men develop it after experiencing a sexual injury. Dr. Pazona explained the classic scenario: “I was with my partner, came out, missed the mark, heard a pop, and then a few months later noticed the curve.” However, not all cases have such a clear cause, and in many instances, no traumatic event is recalled.

What are the Symptoms?

Men with Peyronie’s disease might experience:

Penile curvature: Depending on the scar tissue location, the penis might bend left, right, up, or down.

Pain: This is most common in the early inflammatory phase, which lasts 6-12 months.

Difficulty with sex: Severe curvature (over 60 degrees) can make penetration impossible.

Erectile dysfunction: The scar tissue may hinder blood flow, reducing rigidity.

Management and Treatment

doctor with patient with testicular pain

When it comes to treatment of Peyronie’s disease, options include:

Do Nothing: If it’s not affecting sexual activity or causing distress, no treatment is required.

FDA-Approved Medications: Xiaflex - a collagenase enzyme injected into the plaque to soften and break down scar tissue. This treatment works for about 70% of men, but it requires a commitment to an 8-injection regimen, and patients must abstain from sexual activity during treatment to avoid complications.

Penile Traction Devices: Devices like Restorex, developed at the Mayo Clinic, can help straighten the penis over time by gently stretching the tissue in the opposite direction of the curve. This “physical therapy” requires 30 minutes of use, twice daily, for 12 weeks.

Surgery: Reserved as a last resort for those with severe or persistent curvature. Surgery has risks, including erectile dysfunction and penile shortening, so it’s essential to choose a skilled, fellowship-trained urologist.

Experimental Options: Techniques like shockwave therapy and platelet-rich plasma (PRP) are being explored but lack definitive evidence.

Three Key Takeaways

No Shame in Seeking Help: If you are going through this, it is nothing to be embarrassed about, and you're not alone. Peyronie’s disease affects around 7-9% of men.

Don’t Fall for Shortcuts: Using creams, pills, or trying any DIY methods are not going to be effective. Use tried and tested approaches such as Xiaflex injection or traction devices for best results.

Surgery is a Last Resort: Always exhaust less invasive options first, and seek a highly experienced surgeon if it becomes necessary.

Humor in Healing

Dr. Pazona and Cat injected levity into the topic by discussing the “angle to the dangle” and sharing a lighthearted anecdote about a patient whose partner insisted on keeping a curve that “hit the right spots.” This balance of humor and education makes Balls Deep a must-listen for candid health advice.

If Peyronie’s disease has you or someone you know concerned, don’t wait to consult a healthcare professional. Visit our website for more resources or to book a consultation with Dr. Pazona.

Disclaimer: This podcast and blog are for informational purposes only and do not substitute for professional medical advice. Always seek the guidance of a healthcare provider for any medical concerns.

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